Blood brain barrier and Alzheimer's disease: Similarity and dissimilarity of molecular alerts.

CONCLUSION: The facts from published papers; and technical details of QSAR built up in this study give possibility to formulate the following rules: (i) there are molecular alerts, which are promoters of increase of blood brain barrier and therapeutic activity of anti-Alzheimer disease agents; (ii) there are molecular alerts, which contradict each other. PMID: 29046157 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29046157?dopt=Abstract

Source: Current Neuropharmacology - October 16, 2017 Category: Drugs & Pharmacology Authors: Toropova AP, Toropov AA, Begum S, Achary PGR Tags: Curr Neuropharmacol Source Type: research