Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by 18 F-fluorodeoxyglucose-positron emission tomography: two case reports and a review of the literature

ConclusionsCurrent consensus guidelines recommend all patients with sarcoidosis undergo screening for occult cardiac disease, with thorough history and examination, electrocardiogram, and transthoracic echocardiogram. If any abnormalities are detected, advanced cardiac imaging should follow. While cardiac magnetic resonance imaging identifies the majority of cardiac sarcoidosis, early disease may not be detected. These cases demonstrate18F-fluorodeoxyglucose-positron emission tomography is warranted following an indeterminate or normal cardiac magnetic resonance imaging if clinical suspicion remains high. Unidentified and untreated cardiac sarcoidosis risks significant morbidity and mortality, but early detection can facilitate disease-modifying immunosuppression and cardiac-specific interventions.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research