Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

We describe its structure and function and identify the genes that it targets. PPARγ regulation of inflammation, metabolism, cell fate (proliferation/differentiation/maturation/survival), and many other processes also has relevance to other neurological diseases. Therefore, PPARγ is an attractive target for therapies against a number of progressive neurological disorders.
Source: Progress in Neurobiology - Category: Neuroscience Source Type: research