Effect of Food on the Pharmacokinetics of Saroglitazar Magnesium, a Novel Dual PPAR αγ Agonist, in Healthy Adult Subjects

ConclusionFor the single-dose study, the absorption rate is affected by food as the 90% CI ofCmax is outside 80.00 –125.00%. However, there is no impact of food on the extent of absorption of saroglitazar. The observed lowerCmax of saroglitazar with food has no clinical relevance since the therapeutic efficacy of saroglitazar was achieved after multiple-dose administration, suggesting the importance of total exposure.
Source: Clinical Drug Investigation - Category: Drugs & Pharmacology Source Type: research