p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity

Conclusions: Taking together, we demonstrate here for the first time that Arg-II causes eNOS-uncoupling through activation of p38 mapk in HFD-induced obesity.

http://www.cardiab.com/content/PREACCEPT-1124727874129820

Source: Cardiovascular Diabetology - July 18, 2014 Category: Cardiology Authors: Yi YuAngana RajapakseJean-Pierre MontaniZhihong YangXiu-Fen Ming Source Type: research