Right lobe living donors ages 55 years old and older in liver transplantation

The evidence is insufficient for safe use of elderly donors in adult‐to‐adult living donor liver transplantation (LDLT). The aim of this study was to evaluate the outcomes of right lobe LDLT by donor age (≥55 versus < 55 years). All living donors who underwent right hepatectomy at the authors’ institution between March 2008 and December 2015 were divided into 2 groups: group A with an age ≥ 55 years and group B with an age of <55 years. The selection criteria for elderly donor were preservation of middle hepatic vein, remnant liver volume ≥30%, and no or mild fatty liver. The matching criteria of recipients for the elderly donor grafts were Model for End‐Stage Liver Disease score of <25, graft‐to‐recipient weight ratio of >0.8%, and body mass index of <25 kg/m2. Perioperative data, complications by the Clavien classification, and the outcomes with at least 12 months follow‐up were compared. A total of 42 donors were enrolled in group A and 498 in group B. No significant differences in operative parameters were observed between the 2 groups. The peak postoperative aspartate aminotransferase, alanine aminotransferase, and total bilirubin levels made no difference between the 2 groups. The peak international normalized ratio level was significantly lower in group A than in group B (P = 0.001). All donors recovered completely with no significant differences in overall complications between the 2 groups. All recipients of grafts fro...
Source: Liver Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research