Challenges of conducting a prospective clinical trial for older patients: Lessons learned from NCCTG N0949 (alliance)
Conclusions Challenges were experienced in conducting the first prospective phase III study evaluating progression-free survival of older adults with advanced colorectal cancer receiving palliative chemotherapy with fluoropyrimidine/bevacizumab with or without oxaliplatin in the USA. Future efforts to evaluate treatment outcomes in the older adult population should reflect on lessons learned in this large national effort.
Source: Journal of Geriatric Oncology - Category: Cancer & Oncology Source Type: research
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