An unusual cause of fever in a patient with common variable immunodeficiency

The patient is a 22-year-old man with a history of common variable immunodeficiency (CVID) associated with a heterozygous mutation in TNFRSF13B (TACI), granulomatous lymphocytic interstitial lung disease (GLILD), massive splenomegaly, immune thrombocytopenia, and autoimmune hemolytic anemia. He presented with a 5-day history of fever with temperatures up to 38.9 °C, malaise, sinus congestion, intermittent headaches, and loose stools. He had no cough, dyspnea, vomiting, abdominal pain, joint pain, or rash.

Source: Annals of Allergy, Asthma and Immunology - September 1, 2017 Category: Allergy & Immunology Authors: Andrew T. Dang, Gene Schwartz, LaQuita Jones, Michael J. Absalon, Richard L. McMasters, Amal Assa'ad Tags: Challenging Clinical Cases Source Type: research