Google ’ s Verily is developing AI-powered heart disease test using retinal images

Google (NSDQ:GOOG) parent Alphabet‘s (NSDQ:GOOGL) Verily is developing a new artificial-intelligence powered test that searches for indicators of heart disease risk present in retina images, according to a new study. The study, which has not yet been peer reviewed but has been published by Cornell University, details a new machine-learning powered system designed by Verily to “discover new knowledge from retinal fundus images.” The system operates on data from 284,335 patients, validated on 2 independent datasets of 12,026 and 999 patients, to predict cardiovascular risks “not previously thought to be present or quantifiable in retinal images,” according to the study publication. Researchers claim they were able to use the system to determine a patient’s age accurate to within 3.3 years, gender, smoking status, HbA1c levels, systolic blood pressure and major adverse cardiac events from retinal images. The AI-powered system uses “distinct aspects of the anatomy to generate each prediction,” according to the study, which researchers claim could open up avenues of further research into the technique. Study investigators touted that the system was comparable to the European SCORE risk calculator, but offered the caveat that study came with several limitations, including a “relatively small” dataset size for deep learning. “In particular, although the AUC for cardiovascular events was comparable to SCORE, ...
Source: Mass Device - Category: Medical Devices Authors: Tags: Cardiovascular Imaging Optical/Ophthalmic Research & Development Alphabet Inc. Google Inc. Verily Source Type: news

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Eighty five percent of congenital heart disease patients currently survive to adulthood due primarily to advancements in surgical treatments1. For these survivors with Adult Congenital Heart Disease (ACHD), heart failure (HF) remains the leading cause of death2. Thus, the number of ACHD patients requiring heart transplantation (HT) continues to grow, and with this growth has come improvements in outcomes. In 2009, Lamour et al. demonstrated a 1-year survival of 83% for non-Fontan congenital HT and 71% for patients with Fontan palliation3.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
AbstractLamin A/C gene (LMNA)-related familial dilated cardiomyopathy (fDCM) is an aggressive heart disease that often leads to transplantation and sudden death. The aim of our study was to evaluate the circulating microRNA (miRNA) profiles of patients withLMNA pathogenic mutations. The study population (N = 75) included (i) patients with pathogenicLMNA mutations responsible for fDCM (LMNAMUT), (ii) age- and sex-matchedLMNA wild-type controls (LMNAWT control), and (iii)LMNA wild-type idiopathic DCM (iDCM) patients (LMNAWT iDCM). Detailed clinical information was obtained from each participant. A panel of 179 ...
Source: Journal of Molecular Medicine - Category: Molecular Biology Source Type: research
We report the case of a female patient, 58 years of age, without known heart disease, who underwent liver transplantation without complications. On the second postoperative day, the patient developed cardiogenic shock secondary to stress-induced cardiomyopathy (Takotsubo-like syndrome). The patient was successfully managed with veno-arterial peripheral extracorporeal membrane oxygenation for 6 days, with complete recovery of cardiac function and of the hepatic graft. Coronary syndrome and acute myocarditis were excluded as the causes of the shock. The use of extracorporeal membrane oxygenation in this scenario is possible ...
Source: Revista Brasileira de Terapia Intensiva - Category: Intensive Care Source Type: research
ConclusionsPatients with a bone marrow transplant, solid organ transplant, cancer, or who are admitted to the ICU are at highest risk of VRE bacteremia, particularly at large hospitals and teaching hospitals.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Publication date: Available online 30 June 2018Source: Revista Española de Cardiología (English Edition)Author(s): Pieter van der Bijl, Tomaž Podlesnikar, Jeroen J. Bax, Victoria DelgadoAbstractSudden cardiac death (SCD) accounts for more than 4 million global deaths per year. While it is most commonly caused by coronary artery disease, a final common pathway of ventricular arrhythmias is shared by different etiologies. The most effective primary and secondary prevention strategy is an implantable cardioverter-defibrillator (ICD). The decision to implant an ICD for primary prevention is largely based on a le...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
ConclusionsCHF, acute/chronic kidney injury, PVD and valve disease were significantly associated with increased unexpected ICU admission; patients with CVA suffered increased mortality when admitted to the ICU.
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: Available online 30 May 2018Source: Artificial Intelligence in MedicineAuthor(s): Ion IancuAbstractMediative fuzzy logic is an approach able to deal with inconsistent information providing a solution when contradiction exists. The aim of this paper is to design an expert system based on this type of fuzzy logic in order to diagnose a possible heart disease for a patient. Our proposed system is an extension of the standard Mamdani fuzzy logic controller and contains 44 rules of the type single input–single output. The system works with 11 variables as inputs and one variable as output.Graphical abstract
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research
endon E Abstract Heart failure (HF) is one of the leading causes of death worldwide and has reached epidemic proportions in most industrialized nations. Despite major improvements in the treatment and management of the disease, the prognosis for patients with HF remains poor with approximately only half of patients surviving for 5 years or longer after diagnosis. The poor prognosis of HF patients is in part because of irreparable damage to cardiac tissue and concomitant maladaptive changes associated with the disease. Cell-based therapies may have the potential to transform the treatment and prognosis of HF throug...
Source: Circulation Research - Category: Cardiology Authors: Tags: Circ Res Source Type: research
ConclusionsPatients with a bone marrow transplant, solid organ transplant, cancer, or who are admitted to the ICU are at highest risk of VRE bacteremia, particularly at large hospitals and teaching hospitals.
Source: American Journal of Infection Control - Category: Infectious Diseases Source Type: research
Publication date: Available online 30 June 2018Source: Revista Española de Cardiología (English Edition)Author(s): Pieter van der Bijl, Tomaž Podlesnikar, Jeroen J. Bax, Victoria DelgadoAbstractSudden cardiac death (SCD) accounts for more than 4 million global deaths per year. While it is most commonly caused by coronary artery disease, a final common pathway of ventricular arrhythmias is shared by different etiologies. The most effective primary and secondary prevention strategy is an implantable cardioverter-defibrillator (ICD). The decision to implant an ICD for primary prevention is largely based on a le...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
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