Host cell recruitment patterns by bone morphogenetic protein-2 releasing hyaluronic acid hydrogels in a mouse subcutaneous environment.

CONCLUSION: Hyaluronic acid+BMP-2 gels influenced the inflammatory response in the bone healing microenvironment. Host-derived putative mesenchymal stem cells were major contributors. Addition of hydroxyapatite nanoparticles modified the release pattern of rhBMP-2, resulting in enhanced bone formation. PMID: 28770657 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/28770657?dopt=Abstract

Source: Regenerative Medicine - August 3, 2017 Category: Genetics & Stem Cells Authors: Todeschi MR, El Backly RM, Varghese OP, Hilborn J, Cancedda R, Mastrogiacomo M Tags: Regen Med Source Type: research