The immunomodulatory effects of the Enalapril in combination with Benznidazole during acute and chronic phases of the experimental infection with Trypanosoma cruzi.

In conclusion, we assume that the CT administrated in the initial stage of infection, presents a minor immunomodulatory effect when the VL-10 strain of T. cruzi is used. In contrast, Bz and Enalapril in monotherapies persist suggesting a potential protection against cardiac damages during experimental T. cruzi infection.
PMID: 28720491 [PubMed - as supplied by publisher]

Source: Acta Tropica - July 15, 2017 Category: Infectious Diseases Authors: Leite ALJ, de Paula Costa G, Lopes LR, Dos Reis Mota LW, de Abreu Vieira PM, Talvani A Tags: Acta Trop Source Type: research