Histopathologic Differences Partially Distinguish Syndromic Aortic Diseases
A variety of syndromic diseases such as Marfan syndrome, Loeys-Dietz syndrome, and bicuspid aortic valve with aneurysm along with risk factors of smoking and hypertension result in ascending aortic aneurysms and dissections. Historically, a complicated variety of terms have been used to describe a range of histopathologies that are present in resected specimens. As a result, no consistent patterns of histopathology have been reported. We used the recent SCVP/AECVP consensus statement on nomenclature and diagnostic criteria for noninflammatory aortic disease to blindly evaluate 148 surgically resected specimens.
Source: Cardiovascular Pathology - Category: Cardiology Authors: Kevin M. Waters, Lisa M. Rooper, Andrew Guajardo, Marc K. Halushka Source Type: research
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