Cytopathologic evaluation of patients submitted to radiotherapy for uterine cervix cancer
Summary Cervical cancer is an important public health problem. Pap smear is the leading strategy of screening programs for cervical cancer worldwide. However, delayed diagnosis leads to more aggressive and less effective treatments. Patients with uterine cervix malignancies who are referred for radiotherapy have advanced-stage disease, which results in high rates of locoregional recurrence. The use of radiotherapy as a treatment for cervical cancer causes morphological changes in neoplastic and non-neoplastic epithelial cells, as well as in stromal cells, which make it difficult to diagnose the residual lesion, resulting in a dilemma in cytopathological routine. Based on the difficulties of cytopathologic evaluation for the follow-up of patients treated with radiotherapy for cervical cancer, our objective was to describe the actinic cytopathic effects. Our paper was based on a structured review including the period from June 2015 to April 2016, aiming at an exploratory-descriptive study. Bibliographic investigations were carried out through selection and analysis of articles, list of authors and keywords, selection of new articles focused on the analysis of bibliographic references to previously selected documents, as well as textbooks of recognized merit. The most incident actinic cytopathological alterations as described in the literature are: cellular gigantism, nuclear and cytoplasmic vacuolization, dyskeratosis, bi- and multinucleated (B/M) cells, macro and multiple nucl...
Abstract Male breast cancer (MBC) accounts for 1% of all breast cancer. Adult obesity and tallness are risk factors for MBC, but the role of adolescent fatness is largely unknown. We aimed to assess the association between body mass index (BMI) in adolescence and the incidence of MBC in a large cohort of 16‐19 year‐old Israeli males. 1,382,093 Jewish Israeli males aged 16‐19 who underwent anthropometric measurements, a General Intelligence Test (GIT) and other examinations during 1967‐2011, were followed up to 31.12.2012 for MBC incidence. Cox proportional hazards models assessed the association between adolescent ...
Date: Tuesday, 10 24, 2017; Speaker: Junfang Ji, Professor, Life Science Institute, Zhejiang University; Lei Zhao, Medical Director, Shandong Cancer Hospital/Shandong University; Building: Building 37; 6041/6107
Researchers have found a link between oral sex and smoking and an increased risk of a type head and neck cancer triggered by the human papillomavirus.
CONCLUSION: Highly expressed proteins in malignant pleural effusion were associated with carcinogenesis and cell growth, and proteins associated with tuberculous pleural effusion played a role in the response to inflammation and fibrosis. These findings will aid in the development of novel diagnostic tools for tuberculous pleurisy and malignant pleural effusion of lung cancer. PMID: 29047238 [PubMed - in process]
CONCLUSION: This study provides evidence that PM10 and NO₂ contribute to lung cancer incidence in Korea. PMID: 29047234 [PubMed - in process]
CONCLUSION: Our findings provide specific biological roles of miR-191 in ESCC survival and progression. Targeting the novel miR-191/EGR1 axis represents a potential new therapeutic way to block ESCC development. PMID: 29047233 [PubMed - in process]
Abstract Gut microbiota play critical physiological roles in energy extraction from the intestine and in the control of systemic immunity, as well as local intestinal immunity. Disturbance of gut microbiota leads to the development of several diseases, such as colitis, inflammatory bowel diseases, metabolic disorders, cancer, etc. From a metabolic point of view, the gut is a large metabolic organ and one of the first to come into contact with dietary fats. Interestingly, excessive dietary fat has been incriminated as a primary culprit of metabolic syndrome and obesity. After intake of high-fat diet or Western diet...
New J. Chem., 2017, Accepted Manuscript DOI: 10.1039/C7NJ02252B, PaperGangaraju Gedda, Guan-Rong Chen, Yueh-Yun Yao, Wubshet Mekonnen Girma, Jyun-Dong Li, Chia-Liang Yen, Yong-Chien Ling, Jia-Yaw Chang Dual targeting towards cellular receptors specific to the tumor is an important approach for cancer diagnosis. In this work, we demonstrated the aqueous synthesis of Gd3+-doped CuInS2/ZnS (CIGS/ZnS) quaternary quantum... The content of this RSS Feed (c) The Royal Society of Chemistry
In this study, a... The content of this RSS Feed (c) The Royal Society of Chemistry
A California woman claimed she developed ovarian cancer by using Johnson&Johnson talc-based baby powder for feminine hygiene