An infant presenting with failure to thrive and hyperkalaemia owing to transient pseudohypoaldosteronism: case report.

An infant presenting with failure to thrive and hyperkalaemia owing to transient pseudohypoaldosteronism: case report. Paediatr Int Child Health. 2017 May 30;:1-4 Authors: De Clerck M, Vande Walle J, Dhont E, Dehoorne J, Keenswijk W Abstract A 3-month-old boy presented with failure to thrive and a history of a prenatally detected unilateral hydroureteronephrosis which was confirmed after birth. His growth and developmental milestones had been normal during the first 2 months but in the third month his appetite was poor with reduced intake but no vomiting. At presentation, his temperature was normal, there was mild dehydration and there was weight loss (his weight had decreased by 270 g in the past month). Haemoglobin was 11.9 g/dL, total white cell count 20.2 × 10(9)/L (7-15) [neutrophils 30% (39-75) and lymphocytes 61% (16-47)], platelets 702 × 10(9)/L (150-450), BUN12.1 mmol/L (2.1-16.1), serum creatinine 35.4 μmol/L (15.0-37.1), sodium 126 mmol/L (135-144), potassium 6.8 mmol/L (3.6-4.8), chloride 88 mmol/L (98-106) and bicarbonate 14 mmol/L (19-24). Intravenous rehydration with sodium chloride 0.9% solution was commenced and he was transferred to the paediatric intensive care unit. A salt-wasting syndrome was suspected and a differential diagnosis included adrenal insufficiency, pseudohypoaldosteronism and congenital adrenal hyperplasia (owing to 21-hydroxylase deficiency). Urinalysis confirmed a urinary tract inf...
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research