Preoperative Computed Tomography Scan Analysis of Interleaflets Triangles to Guide Aortic Root Repair Procedures.

CONCLUSIONS: Based on experience acquired in the operating room, the acute-angle subcommissural triangles were considered normal, the equilateral triangles mildly dilated, and the obtuse triangles severely dilated. According to this classification, different reparative approaches were selected. A CTscan 3D reconstruction method, as validated by the present data, allows a preoperative evaluation of the triangles and VAJ in order to best plan a surgical reparative approach tailored to a single patient. PMID: 28544826 [PubMed - in process]
Source: Journal of Heart Valve Disease - Category: Cardiology Tags: J Heart Valve Dis Source Type: research

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Several indicators on pretreatment FDG-PET/CT scans can help predict overall...Read more on AuntMinnie.comRelated Reading: Biomarkers on PET, MRI show breast cancer risk FDG-PET/CT within a year of heart valve surgery looks safe FDG-PET/CT helps predict tuberculosis relapse 2 new PET tracers may best FDG in cancer imaging FDG-PET/CT aids in melanoma treatment assessment
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
ConclusionPredicting overall readmissions after open ‐heart valve surgery is difficult as causes of readmissions vary and different causes are associated with different characteristics. Future studies should target reducing cause‐specific readmissions.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: ORIGINAL ARTICLE Source Type: research
We thank Cannata and Russo for their letter1 discussing the definition of geometric orifice area (GOA) of prosthetic heart valves provided in the recently published Position Statement of  the European Association for Cardio-Thoracic Surgery–Society of Thoracic Surgeons–American Association for Thoracic Surgery (EACTS-STS-AATS) Valve Labelling Task Force.2
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Letter to the Editor Source Type: research
The objective of this study is to evaluate the hemodynamic characteristics and the turbulent properties of a fetal sized trileaflet transcatheter pulmonary valve in comparison with an adult balloon-expandable valve in order to assess the possibility of designing valves for fetal applications using dynamic similarity. A 6 mm fetal trileaflet valve and a 26 mm SAPIEN 3 valve were assessed in a pulse duplicator. Particle image velocimetry was performed. Pressure gradient (ΔP), effective orifice area (EOA), regurgitant fractions (RF), pinwheeling indices (PI) and turbulent stresses were evaluated. ΔP...
Source: Annals of Biomedical Engineering - Category: Biomedical Engineering Authors: Tags: Ann Biomed Eng Source Type: research
AbstractDegradable heart valves based on in situ tissue regeneration have been proposed as potentially durable and non-thrombogenic prosthetic alternatives. We evaluated the acute in vivo function, microstructure, mechanics, and thromboresistance of a stentless biodegradable tissue-engineered heart valve (TEHV) in the tricuspid position. Biomimetic stentless tricuspid valves were fabricated with poly(carbonate urethane)urea (PCUU) by double-component deposition (DCD) processing to mimic native valve mechanics and geometry. Five swine then underwent 24-h TEHV implantation in the tricuspid position. Echocardiography demonstr...
Source: Journal of Cardiovascular Translational Research - Category: Cardiology Source Type: research
This study is aimed to improve a biological tissues cryopreservation by adding a new heat transfer fluid - polydimethylsiloxane (PDMS). To evaluate its efficiency the porcine biological tissues (heart valves, aortic and trachea fragments) were cryopreserved and thawed in low-viscous PDMS. According to the computer simulation, the midsection cooling rate was up to 490 °C/min and the midsection thawing rate was up to 1140 °C/min with admissible temperature uniformity. Cryoprotectants and liquid nitrogen were not used. The quality of tissue cryopreservation was evaluated using a number of histological and immunohi...
Source: Cryobiology - Category: Biology Authors: Tags: Cryobiology Source Type: research
Patient-specific 3D-printed coronary models have allowed clinicians to determine...Read more on AuntMinnie.comRelated Reading: 3 ways to advance 3D printing in radiology AR, 3D printing make waves in cardiac care 3D printing helps unravel rare cardiac anomalies 3D printing technique improves heart valve sizing 3D printing gives pediatric heart surgery a boost
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Elena Aikawa, MD, PhD, director of the Heart Valve Translational Research Program in the Division of Cardiovascular Medicine, and Su Ryon Shin, PhD, of the Division of Engineering in Medicine, received the Brigham Department of Medicine ’s 2020 Innova
Source: BWH News - Category: Hospital Management Source Type: news
This study describes work to develop dynamic computer models of BHVs in the aortic test section of an experimental pulse-duplicator platform that is used in academia, industry, and regulatory agencies to assess BHV performance. These computational models are based on a hyperelastic finite element extension of the immersed boundary method for fluid-structure interaction (FSI). We focus on porcine tissue and bovine pericardial BHVs, which are commonly used in surgical valve replacement. We compare our numerical simulations to experimental data from two similar pulse duplicators, including a commercial ViVitro system and a cu...
Source: Annals of Biomedical Engineering - Category: Biomedical Engineering Authors: Tags: Ann Biomed Eng Source Type: research
This study represents a further step towards the use of personalized simulations to virtually plan TAVI, aiming at improving not only the efficacy of the implantation but also the exploration of “off-label” applications as the TAVI in the setting of BAV patients.Graphical abstractComputational frameworks of TAVI in patients with stenotic bicuspid aortic valve
Source: Medical and Biological Engineering and Computing - Category: Biomedical Engineering Source Type: research
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