Short-term effects of green tea chronotherapy on the metabolic homeostasis of mice on different diets.

The objective of this study was to evaluate how the administration of C. sinensis at different times of day influenced changes in body weight, blood glucose levels, and food intake of mice kept under different diet conditions. The structural organization of abdominal adipose tissue was also evaluated, as were certain aspects of lipid metabolism and overall synthetic activity in the liver, adipose tissue, and ovaries. The results obtained suggest that the intake of green tea in the light phase of the day stimulates weight loss, regardless of the diet ingested. Neither glucose levels nor the structural organization of adipose tissue was found to be altered in any of the experimental groups. Neither diet nor the time at which the green tea was administered was found to have any effects on the amount of food the mice consumed. The time at which green tea was consumed and the type of diet both influenced LXRαβ nuclear receptor expression, as well as the expression of fibrillarin in the liver and ovaries, although this influence was tissue specific. PMID: 28510251 [PubMed - in process]
Source: Genetics and Molecular Research - Category: Genetics & Stem Cells Authors: Tags: Genet Mol Res Source Type: research