Ludwig researchers identify counterintuitive approach to treating a brain cancer

(Ludwig Institute for Cancer Research) The loss of the tumor suppressor gene PTEN has been linked to tumor growth and chemotherapy resistance in the almost invariably lethal brain cancer glioblastoma multiforme (GBM). Now, Ludwig researchers have shown that one way to override the growth-promoting effects of PTEN deletion is, surprisingly, to inhibit a separate tumor suppressor gene.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news