Castleman disease with follicular dendritic cell sarcoma presenting with pseudotumor cerebri and myasthenia gravis (P5.189)

Conclusions:To our knowledge, this is the first reported case of unicentric CD with FDCS presenting with PTC and MG. A potential unifying pathophysiology could involve the elevation of interleukin-6, which has been previously described to contribute to lymphoproliferation associated with cases of CD and CD with MG. Elevated IL-6 levels in serum and CSF have been noted in PTC, which may be a linking factor to CD or an epiphenomenon.Disclosure: Dr. Fein has nothing to disclose. Dr. Trejo Bittar has nothing to disclose. Dr. Shende has nothing to disclose. Dr. Scalzetti has nothing to disclose. Dr. Ko has nothing to disclose.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Fein, A., Bittar, H. T., Shende, M., Scalzetti, E., Ko, M. Tags: Neuro-ophthalmology/Neuro-otology I Source Type: research