Correlation between MRI cerebral white matter changes, muscle structure and/or muscle function in myotonic dystrophy type 1 (DM1) (P3.113)

Conclusions:Correlations between global cerebral FA and muscle structure/function suggests a CNS role in DM1 neuromuscular dysfunction.Study Supported by: This study was supported by the National Institutes of Neurologic Disorders and Stroke (NINDS) grant 1R01NS094387, the National Center for Advancing Translational Sciences (NCATS) grant 1U54TR001356-01 The University of Iowa Clinical and Translational Science Award.Disclosure: Dr. Smith has nothing to disclose. Dr. Nopoulos has nothing to disclose. Dr. Shields has nothing to disclose. Dr. Thedens has nothing to disclose. Dr. Gutmann has nothing to disclose.

Source: Neurology - April 17, 2017 Category: Neurology Authors: Smith, C., Nopoulos, P., Shields, R., Thedens, D., Gutmann, L. Tags: Myopathies & amp;amp; Myasthenia Gravis III Source Type: research