Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice

In conclusion, butyrate and its more palatable synthetic derivative, FBA, modulating mitochondrial function, efficiency, and dynamics, can be considered a new therapeutic strategy to counteract obesity and insulin resistance.

Source: Diabetes - April 20, 2017 Category: Endocrinology Authors: Mollica, M. P.; Mattace Raso, G.; Cavaliere, G.; Trinchese, G.; De Filippo, C.; Aceto, S.; Prisco, M.; Pirozzi, C.; Di Guida, F.; Lama, A.; Crispino, M.; Tronino, D.; Di Vaio, P.; Berni Canani, R.; Calignano, A.; Meli, R. Tags: Pharmacology and Therapeutics Source Type: research