Funtabulously Frivolous Friday Five 185

LITFL: Life in the Fast Lane Medical Blog LITFL: Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog Just when you thought your brain could unwind on a Friday, you realise that it would rather be challenged with some good old fashioned medical trivia FFFF…introducing Funtabulously Frivolous Friday Five 185 with an Easter twist. Question 1 Where was Rapamycin discovered? + Reveal the Funtabulous Answer expand(document.getElementById('ddet751945380'));expand(document.getElementById('ddetlink751945380')) Easter Island (Papa Nui) If you are lucky enough to climb upto the extinct volcano Rano-Kau on Easter Island you will discover a plaque commemorating the discovery of Rapa-mycin. Found in the soil on Rapa Nui and originally marketed as an antifungal but had some side effects, most notably its potent immunosuppressive and antiproliferative properties. It is now used to prevent organ rejection in transplant patients (prevents activation of T cells and B cells by inhibiting interleukin-2), coronary stent coating (eliminates abnormal white cells) and is used in the treatment of autoimmune lymphoproliferative syndrome (ALPS). Also if you are lucky enough to be a mouse then it will increase your life expectancy, however due to its immunosuppressant proerties I wouldn’t go ordering it over the internet just yet. [Reference] Question 2 Who gets the most traumatic auricular amputations at this time of year? + Reveal the Funtabu...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Frivolous Friday Five auricular amputations bunny chocolate easter easter island egg on a string rabbit Rapamycin theobromine transposition of the great arteries tularemia Source Type: blogs