'When I met Chloe she was dead': one girl, four hearts and an NHS miracle
Chloe Narbonne ’s heart failed when she was 11, starting a near-hopeless fight for survival. A year on from groundbreaking surgery, she is alive and this is her storyRevealed: girl of 13 is first child in Britain to receive artificial heart“By the time I met Chloe she was dead,” André Simon says matter-of-factly. “I told her parents clearly that she didn’t really have a chance to survive. What I was proposing gave her a theoretical chance.” He pauses. “But I also said that the operation might just prolong her agony and su ffering – I didn’t even know if she would survive it – and that it was OK just to let her go.”Simon, one of the world ’s leading heart and lung specialists, is recalling the conversation he had at the beginning of May last year with Fabienne Narbonne and Todd Jancey that led to him implanting an artificial heart inside their 12-year-old daughter Chloe. “It was an emotional meeting, it was tense, it was horrible . They were trying to be calm but they were extremely anxious and were holding on to each other for support. They put their last hopes in me and they prayed for a miracle.”Continue reading...
The week of April 23-27 has been designated as National Pediatric Transplant Week. This week is to bring attention to the great need for organ donations and to honor donors and their families whose incredibly selfless gift has given someone the gift of life.While most of us will never experience the need for a transplant, there are many of us who know someone who has a debilitating condition such as kidney dialysis that are in need of a transplant.Right now there are almost 2,000 children on the national transplant list. Those needing hearts, lungs, eyes, tissue, liver, kidney, or some other body part are...
650,000 renal, hepatic, and cardiothoracic (heart and/or lung) transplants have been performed in the U.S. since 1988, with UNOS reporting a 20% increase in transplants between 2012 through 2016. The immunosuppression vital to maintaining graft survival comes with a 65-200X greater frequency of SCC compared to the non-transplant population. These SCC exhibit more aggressive behavior, withincreased morbidity and mortality. The aim of this study was to investigate the impact of rejection on the incidence and presentation of SCC.
Organs donated from people infected with hepatitis C can be safely transplanted, and any transmission of the virus can be treated with antiretrovirals, new research shows.Medscape Medical News
In his book, The Checklist Manifesto: How to Get Things Right, Atul Gawande describes the origins of the checklist that involved the airline industry beginnings of the B-17 airplane.1 The test plane ’s flight ended in a deadly crash deemed due to pilot error. The B-17 was felt to be too much plane for one pilot and was abandoned as the next generation long-range bomber for the U.S. military. A persistent group of pilots developed a checklist of tasks to be performed for each phase of flight t ake-off, inflight, and landing.
ConclusionsTranscatheter LA decompression is an age-independent, effective palliation treating patients with HFpEF.
This study demonstrates that small peptide domains derived from native protein amelogenin can be utilized to construct a mineral layer on damaged human enamel in vitro. Six groups were prepared to carry out remineralization on artificially created lesions on enamel: (1) no treatment, (2) Ca2+ and PO43- only, (3) 1100 ppm fluoride (F), (4) 20 000 ppm F, (5) 1100 ppm F and peptide, and (6) peptide alone. While the 1100 ppm F sample (indicative of common F content of toothpaste for homecare) did not deliver F to the thinly deposited mineral layer, high F test sample (indicative of clinical varnish treatment) formed mainly C...
Pulmonary artery anastomosis stenosis is a rare cause of right ventricular failure after orthotopic heart transplantation. In this case report, direct ultrasound of the pulmonary artery helped diagnose stenosis at a location not visible on transesophageal echocardiography or even with standard epicardial ultrasound views. It is important to evaluate all vascular anastomoses after heart or lung transplantation because surgical revision of these lesions is facile, but if left undiagnosed, significant morbidity or mortality is likely.