Effect of Testosterone Replacement Therapy on Vitamin D and FGF-23 Levels in Congenital Hypogonadism.

CONCLUSIONS: The results show that a short term TRT increases plasma FGF-23 and ADMA levels, in young, treatment naive patients with CHH. Whether this is an early implication of TRT related adverse effects in this very young and treatment naïve population of CHH is not clear. Future prospective studies are required to find out the long-term effects of TRT on cardio-metabolic morbidity and mortality in this specific population.
PMID: 28230890 [PubMed - as supplied by publisher]

Source: Endokrynologia Polska - February 22, 2017 Category: Endocrinology Authors: Haymana C, Sonmez A, Aydogdu A, Tapan S, Basaran Y, Meric C, Baskoy K, Taslipinar A, Yilmaz MI, Azal O Tags: Endokrynol Pol Source Type: research