Holistic Medicine for the Brain

Mind Expansion? There is a slowly growing body of support for certain hallucinogenic serotonin-like molecules supporting cognitive gains, antidepressant effects and changes in brain areas related to attention, self-referential thought, and internal mentation. These molecules are present inVirola Ayahuascaand used in traditional native South American medicine.Here researchers found thatin silico systems biology analyses support 5- MeO-DMT ’s anti-inflammatory effects and reveal a modulation of proteins associated with the formation of dendritic spines, including proteins involved in cellular protrusion formation, microtubule dynamics and cytoskeletal reorganization. Proteins involved in long-term potentiation were modulated in a co mplex manner, with significant increases in the levels of NMDAR, CaMKII and CREB, but a reduction of PKA and PKC levels. These results offer possible mechanistic insights into the neuropsychological changes caused by the ingestion of substances rich in dimethyltryptamines: Vanja Dakic, Juliana Minar di Nascimento, Rafaela Costa Sartore, Renata de Moraes Maciel, Draulio B. de Araujo, Sidarta Ribeiro, Daniel Martins-de-Souza , Stevens Rehen.Short term changes in the proteome of human cerebral organoids induced by 5-methoxy-N,N-dimethyltryptamine. bioRxiv preprint first posted online Feb. 13, 2017; doi: http://dx.doi.org/10.1101/108159...anti-5-HT2A (RA24288, Neuromics)...Images: Cerebral organoids express 5-MeO-DMT receptors and different cell ...
Source: Neuromics - Category: Neuroscience Tags: 5-methoxy-N 5HT Antibodies 5HT2AR Antibody Depression Human Neural Progenitors N-dimethyltryptamine Serotonin Source Type: news