Postmenopausal hormone therapy exceeding ten years may protect from dementia
(University of Eastern Finland) Postmenopausal estrogen-based hormone therapy lasting longer than ten years was associated with a decreased risk of Alzheimer's disease in a large study carried out at the University of Eastern Finland. The study explored the association between postmenopausal hormone replacement therapy, Alzheimer's disease, dementia and cognition in two nation-wide case-control studies and two longitudinal cohort studies. The largest study comprised approximately 230,000 Finnish women and the follow-up time in different studies was up to 20 years.
VASCULAR dementia symptoms include memory loss and mood changes. It is the second most common form of dementia after Alzheimer ’s disease. Signs, causes and whether stroke can bring on the condition.
CONCLUSIONS Our novel approach showed APOE as a common gene signature with a link to dementia, MetS, and diabetes. Future gene association studies should focus on the association of gene polymorphisms with multiple disease models to identify novel putative drug targets. PMID: 29229897 [PubMed - in process]
A progressive new research programme has just been funded by UK Dementia Research Institute (UK DRI), in its first investment in Huntington ’s disease since the Institute was established last year.
There are a handful of basic strategies that can substantially reduce your risk for developing cognitive decline and Alzheimer’s dementia, simple strategies that you can initiate on your own. They are certainly far more effective than prescription drugs for dementia which do almost nothing for memory and have NO impact on progression of the disease. About Undoctored: We are entering a new age in which the individual has astounding power over health–but don’t count on the doctor or healthcare system to tell you this. We draw from the health information of the world, collaborate, share experiences, colle...
Publication date: Available online 14 December 2017 Source:Journal of Geriatric Oncology Author(s): Jon Snaedal Cancer and impaired cognition are both frequent conditions in old age and consequently coexist to certain degree. The prevalence of impaired cognition increases sharply after the age of 65 and the more advanced form of cognitive impairment; dementia, is exceeding 30% by the age of 85years. Adequate cognition is crucial for understanding important facts and for giving consent for intervention. There are many different stages of cognitive impairment, ranging from subjective cognitive impairment to severe dementia....
AbstractStrong evidence is available suggesting that effective reduction of exposure to demonstrated modifiable risk factors in mid-life or before could significantly decrease the incidence of Alzheimer ’s disease (AD) and delay its onset. A key ingredient to achieving this goal is the reliable identification of individuals at risk well before they develop clinical symptoms. The aim of this study was to provide further neuroimaging evidence of the effectiveness of a validated tool, the ANU Alzhei mer’s Disease Risk Index, for the assessment of future risk of cognitive decline. Participants were 461 (60–64...
At least 1,400 vulnerable people will spend Christmas on a hospital ward - well enough to go home, but trapped because of a social care system starved of funding.
DEMENTIA is best treated when caught early. These are the four early symptoms to look out for in elderly relatives this Christmas.
DEMENTIA and stroke risk could be increased by drinking diet soft drinks daily, researchers have claimed. The risk of developing Alzheimer ’s disease increased almost three times compared to those that don’t drink diet fizzy drinks.
CONCLUSIONS: Through team collaboration and engagement of others in the community who work with Latinos with dementia, we believe this process allowed us to successfully create culturally appropriate informational materials that address a sensitive topic for Hispanic/Latino families. CLINICAL IMPLICATIONS: Brain tissue is needed to further knowledge about underlying biological mechanism of neurodegenerative diseases, however it is a sensitive topic. Materials assist with family discussion and facilitate the family's follow-through with BD. PMID: 29227743 [PubMed - as supplied by publisher]