The Risk of Ischemic Cardio- and Cerebrovascular Events Associated with Oxycodone –Naloxone and Other Extended-Release High-Potency Opioids: A Nested Case–Control Study

ConclusionsOur study does not indicate an association between oxycodone –naloxone and ischemic cardio- or cerebrovascular events. However, our findings do suggest that every change in ER HPO therapy should be conducted with caution.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research