High-risk patient gets life-saving transplant when UCLA team accepts her case
A 24-year-old cystic fibrosis patient is starting the new year with new hope thanks to help from the U.S. Air Force, the actor who played Chewbacca in the “Star Wars” movies and a UCLA surgeon who said yes to a high-risk case.Kathlyn Chassey of San Antonio, Texas, was born with cystic fibrosis, a genetic disease characterized by the build-up in the lungs of thick, sticky mucus that traps infection-causing bacteria. While there is no cure, lung transplantation can help alleviate many of the symptoms.Courtesy of the Chassey familyKathlyn Chassey walks after her lung transplant surgery at Reagan UCLA Medical Center.Chassey ’s father, Chris, is a chief master sergeant in the United States Air Force. Last November, when her breathing problems worsened, she was hospitalized at the Brooke Army Medical Center in San Antonio. By the end of the month, her condition became critical, and she was placed on life support to tak e over her breathing function.The only chance of saving her life, doctors warned, was a lung transplant.An urgent search began to find a transplant center that would take her case. But one center after another turned her down, deeming the surgery too risky.With time running out, Chassey ’s family desperately needed help spreading the word. Friends quickly developed a website and social media campaign. As members of the "Star Wars" fandom, the family turned to longtime friend, actor Peter Mayhew — Chewbacca from the films &...
Authors: Hsin MKY, Wong CF, Yan SW, Fan KY, Ho CKL, Bhatia I, Au TWK Abstract Clinical lung transplant was first performed in Hong Kong in 1995. In the early years, the volume of activity was very low. There has been a clear trend of increasing volume in the past few years. The recipient pathology is very different from the International Society for Heart and Lung Transplantation (ISHLT) database, with complete absence of cystic fibrosis and alpha-1-antitrypsin deficiency, and a predominance of diseases of the pulmonary circulation. Lymphangioleiomyomatosis (LAM) has a much higher representation on the waiting list...
Claire Wineland vowed she wouldn't have a lung transplant, but her decline from cystic fibrosis made her reconsider. Now she's fighting for a chance at survival.
In this study we investigated regulatory t cells after combined lung and liver transplantation, or after isolated lung transplantation, in cystic fibrosis patients and correlated the findings with long term outcomes
Patients with cystic fibrosis (CF) may have pulmonary infection with multi-drug resistant organisms (MDRO) potentially impacting post-transplant mortality. Our objective was to study 1-year mortality in CF patients with MDRO compared to those without MDRO lung transplant recipients (LTR) querying the largest international registry.
Early detection of Mycobacterium abscessus complex (MABSC) is crucial for patients with chronic lung disease to enhance the opportunity for potential eradication. Colonisation with MABSC is an absolute contra indication to lung transplantation in many transplant centres. Isolation of MABSC and other non-tuberculous mycobacteria (NTM) by traditional AFB culture is problematic, particularly from patients with cystic fibrosis (CF). Cultures are frequently overgrown by other bacteria or fungi and sputum decontamination procedures can reduce the viability of NTM.
Lobar lung transplantation is known as an alternative for higher Donor/Receiver mismatch in cystic fibrosis or idiopathic pulmonary fibrosis patients. Using lobar lung transplantation for Pulmonary Hypertension remains questionable because of the higher risk of primary graft dysfunction. We thought to determine wether lobar lung transplantation from brain-dead donors is an option for Pulmonary Hypertension.
This study aims to characterize this acute airway inflammation in association with ACR status.
We report our experience of LTx for CF patients infected with BCC.
Achromobacter colonization of cystic fibrosis (CF) patients is deemed to be associated with higher risk of graft loss and the rods are usually defined as multi or pan resistant. We aimed to evaluate if CF patients transplanted with previous Achromobacter colonization had worst clinical outcome post lung transplantation.