Cannabinoid Type-2 Receptor Drives Neurogenesis and Improves Functional Outcome After Stroke [Basic Sciences]

Conclusions—Our data support that CB2R is fundamental for driving neuroblast migration and suggest that an endocannabinoid tone is required for poststroke neurogenesis by promoting neuroblast migration toward the injured brain tissue, increasing the number of new cortical neurons and, conceivably, enhancing motor functional recovery after stroke.

Source: Stroke - December 22, 2016 Category: Neurology Authors: Isabel Bravo–Ferrer, Maria I. Cuartero, Juan G. Zarruk, Jesus M. Pradillo, Olivia Hurtado, Victor G. Romera, Javier Diaz–Alonso, Juan M. Garcia–Segura, Manuel Guzman, Ignacio Lizasoain, Ismael Galve–Roperh, Maria A. Moro Tags: Stem Cells, Pharmacology, Neurogenesis Original Contributions Source Type: research