Clopidogrel and ischemic stroke outcomes by smoking status: Smoker's paradox?

Active smokers with myocardial infarction were shown to have enhanced benefit with clopidogrel compared with aspirin. Whether this “paradox” exists in ischemic stroke patients is unknown. We aimed to investigate whether smoking status has a differential impact on the efficacy of clopidogrel vs. aspirin in patients with non-cardioembolic strokes.
Source: Journal of the Neurological Sciences - Category: Neurology Authors: Source Type: research