Prescribing of baclofen for alcohol dependence 'should be reconsidered'

(European College of Neuropsychopharmacology) The drug baclofen has received high visibility as a possible breakthrough treatment for alcohol dependence. Now a new randomised controlled trial from the University of Amsterdam found no evidence for the usefulness of high-dose baclofen in treating alcoholism when added to psychosocial treatments.
Source: EurekAlert! - Social and Behavioral Science - Category: Global & Universal Source Type: news

Related Links:

Publication date: Available online 17 September 2018Source: European Polymer JournalAuthor(s): Salim Ok, Ahmet AltunAbstractThe interactions between tannic acid (TA), a natural bioactive polyphenol, and two biodegradable polymers have been investigated in presence and absence of a pyrazole derivative through their NMR and UV-Vis spectra as well as quantum chemical calculations. The goal of the current contribution is to identify different H-bonds for revealing a “two-molecules” carrier system, and to compare molecular carrier capability of two different biodegradable polymers. The role of H-bonding ability of o...
Source: European Polymer Journal - Category: Chemistry Source Type: research
Publication date: Available online 17 September 2018Source: Journal of Hospital InfectionAuthor(s): Thibaud Vermeil, Alexandra Peters, Claire Kilpatick, Daniela Pires, Benedetta Allegranzi, Didier PittetAbstractHealthcare-associated infections (HAI) affect hundreds of millions of individuals worldwide. Performing hand hygiene is widely accepted as a key strategy of infection prevention and control (IPC) to prevent HAI, as healthcare workers’ contaminated hands are the vehicle most often implicated in the cross-transmission of pathogens in healthcare. In the last 20 years, a paradigm shift has occurred in hand hygiene...
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
1. Cancer is not rare.  Technically, childhood cancer is rare compared to adult cancer, but it’s not as rare as you think.   Outside of my work, I can think of 3 people who I know personally that had a childhood cancer.  A teammate on my high school basketball team, my sister-in-law, and a high school debate teammate.   My guess is that you also know someone from church, a coworker’s kid, or one of your kids’ classmates who has been affected by this disease. 2. Curing cancer and preventing cancer is not the same thing.  We do have a cure for the majority of childhood cancers....
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Oncology/Hematology Pediatrics Source Type: blogs
ConclusionsECS is related to a worse outcome regarding control of all seizure types, persistence of EM, and higher frequency of limb myoclonia, as well as the total number of TCS and/or MTCS.
Source: Seizure - Category: Neurology Source Type: research
The objective of the present study was to retrospectively survey the demographic and clinical profiles of 1,534 patients diagnosed with candidiasis and treated at the Center for Diagnosis of Oral Diseases (CDOD), Pelotas Dental School, Federal University of Pelotas between 1997 and 2014. Using a retrospective, cross-sectional, epidemiological design, data on race, gender, age, systemic diseases, oral candidiasis type and location, symptoms, and harmful habits such as smoking and alcohol consumption were collected. The statistical analysis was performed using STATA version 13.1. Risk factors for chronic atrophic candidiasis...
Source: Brazilian Oral Research - Category: Dentistry Source Type: research
Publication date: 15 January 2019Source: Journal of Molecular Structure, Volume 1176Author(s): P. Tamizhdurai, Subramanian Sakthinathan, P. Santhana Krishnan, A. Ramesh, V.L. Mangesh, A. Abilarasu, S. Narayanan, K. Shanthi, Te-Wei ChiuAbstractZirconium incorporated mesoporous SBA-15 silica with Si/Zr ratios of 10, 20, 30 and 40 have been synthesized under hydrothermal conditions. The prepared mesoporous materials were characterized by suitable physical and chemical characterization technique. Besides, the catalytic activity of the prepared SBA-15/ZrO2 (10–40%) catalyst was used for benzyl alcohol oxidation with terti...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research
CONCLUSIONS The prevalence of alcohol-related disorders in the rural population is high, but, on average, it is lower than that found in urban populations. Risk and protective factors were similar to those found in previous studies. Men, younger persons, and smokers are at higher risk for alcohol-related disorders. On the other hand, practicing a religion and having a higher education level were protective factors.RESUMO OBJETIVO Descrever a preval ência de transtornos relacionados ao uso de álcool e fatores associados em uma população exclusivamente rural. MÉTODOS Estudo transversal de ba...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
ABSTRACT OBJECTIVE To estimate the prevalence of smoking and associated factors among rural residents. METHODS This is a population-based, cross-sectional study of 1,519 individuals carried out in 2016. We randomly selected 24 of the 50 census tracts that make up the eight rural districts of the city of Pelotas, State of Rio Grande do Sul, Brazil. All individuals aged 18 years or more living in the randomly selected households were eligible. Smokers were all those who smoked ≥ 1 cigarette/day for at least one month or declared that they had stopped smoking for less than one month. The independent variables included soci...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
CONCLUSIONS The previous detailed recognition of the research environment was crucial for decision making as the maps and territory had geographical inconsistencies. The strategies and techniques used in studies for the urban area are not applicable to the rural area given the outcomes observed in Pelotas. The decisions taken, keeping the methodological rigor, were essential to ensure the timely execution of the study with the financial resources available.RESUMO OBJETIVO Descrever o planejamento, a amostragem, os aspectos operacionais do campo e a amostra obtida durante pesquisa realizada na zona rural, especificando e di...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
“Drugs are a waste of time. They destroy your memory and your self-respect and everything that goes along with your self-esteem.” – Kurt Cobain I grew up in a close-knit, fairly religious family where children were seen and not heard, where mealtime meant everyone sat down together and exchanged pleasantries while enjoying the prepared-at-home repasts, complete with dessert. There was no distraction, either from television or radio, and the telephone ringing was a rare occurrence, quickly dispatched once the caller learned we were eating. In fact, nothing was so urgent back then. It was, indeed, a peacefu...
Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Substance Abuse Alcoholism Drug Abuse Opioid Addiction Source Type: news
More News: Alcoholism | Baclofen | International Medicine & Public Health | Neurology | Neuroscience | Science