Evidence of microbiota dysbiosis in chronic rhinosinusitis

ConclusionBacterial community dysbiosis was more apparent than specific associations with examined phenotypes or endotypes, and may play a role in the pathogenesis or influence the severity of CRS. Reductions in several common core bacterial taxa, increased inter‐ and intrasubject variability, reduced bacterial diversity, and increased bacterial load characterized aberrant bacterial communities in CRS.

Source: International Forum of Allergy and Rhinology - October 31, 2016 Category: Allergy & Immunology Authors: Michael Hoggard, Kristi Biswas, Melissa Zoing, Brett Wagner Mackenzie, Michael W. Taylor, Richard G. Douglas Tags: ORIGINAL ARTICLE Source Type: research