Circadian Melatonin Rhythm Following Traumatic Brain Injury

Conclusions: In patients with TBI, melatonin production was attenuated overnight, and the timing of melatonin secretion was delayed. We suggest that disruption to the circadian regulation of melatonin synthesis is a feature of severe TBI, possibly contributing to the sleep difficulties that are commonly reported in this population.

Source: Neurorehabilitation and Neural Repair - September 29, 2016 Category: Neurology Authors: Grima, N. A., Ponsford, J. L., St. Hilaire, M. A., Mansfield, D., Rajaratnam, S. M. Tags: Clinical Research Articles Source Type: research