Bispectral index under propofol anesthesia in children: a comparative randomized study between TIVA and TCI

ConclusionsPropofol administration using manual infusion guided by clinical signs was associated with higher risks of over‐ or underdosage when compared to BIS‐guided administrations. When propofol infusion was guided by the BIS, no major difference was found between TIVA and TCI (either with the Kataria or the Schnider model). This study highlights the need of a pharmacodynamic feedback during propofol anesthesia in children.

Source: Pediatric Anesthesia - July 26, 2016 Category: Anesthesiology Authors: Nicolas Louvet, Agn ès Rigouzzo, Nada Sabourdin, Isabelle Constant Tags: Research Report Source Type: research