Identification of potential therapeutic targets in human head & neck squamous cell carcinoma.

Conclusion Five genes and their products may serve as a diagnostic biomarker or therapeutic target for HNSCC. While additional work is needed to elucidate the biological significance of these proteins, CD24 and CD74 expressed only in small proportion of cells indicating tumor heterogeneity and subtypes of tumor initiating cells (CD24+/CD44+) present in HNSCC.
Source: Head and Neck Oncology - Category: Cancer & Oncology Source Type: research