Effect of cholesterol medicine on inflammatory diseases mapped

The cholesterol medicine simvastatin, which is one of the most commonly used pharmaceuticals in the world, also has a beneficial effect on the immune defense system with regard to diseases such as type 1 diabetes, multiple sclerosis and rheumatoid arthritis. Researchers have now explored why this is so, and their findings may result in improved treatment.
Source: ScienceDaily Headlines - Category: Science Source Type: news

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Conclusions Moderate-to-vigorous intensity physical activity is an important predictor of cardiometabolic health in early adulthood. Strategies to prevent declines in MVPA at this life stage are required to prevent deteriorating cardiometabolic health profiles.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: EPIDEMIOLOGY Source Type: research
Conclusion These findings demonstrate that T2D and HTN attenuate tolerance to uncompensable heat stress (32°C WBGT); however, these chronic diseases do not significantly impact thermal and cardiovascular strain, or the validity of ACIGH recommendations during moderate-intensity work.
Source: Medicine and Science in Sports and Exercise - Category: Sports Medicine Tags: APPLIED SCIENCES Source Type: research
In conclusion, awareness of the risk factors associated with IFIS, their detailed preoperative assessment and intraoperative measures and surgical intervention is crucial in addressing IFIS. Lack of awareness can turn a routine, uneventful surgery into one with significant visual morbidity.
Source: International Ophthalmology - Category: Opthalmology Source Type: research
WHETHER it's general aches and pains, stomach problems or just feeling under the weather, ibuprofen is taken daily by millions of people worldwide. Ibuprofen also treats inflammation such as strains and sprains, and pain from arthritis. Most side effects are minimal or non-existent. However, research has found that spotting a serious sign when you go to the toilet should mean that you stop taking the painkiller.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Exclusive: NHS launching large trial of approach that could boost number of transplants and their success rateThousands of lives could be saved globally by giving patients a 10p statin before transplants, doctors have said, as the NHS launches the world ’s largest clinical trial in organ donors.The medical breakthrough is predicted to dramatically increase the supply of organs for transplant. Currently, demand for organs vastly exceeds the number available. Every year thousands of people die waiting for a transplant, including hundreds in Britain.Continue reading...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Organ donation Statins Medical research NHS Health Society Science UK news Source Type: news
In conclusion, inhibiting the lysosomal oxidation of LDL in atherosclerotic lesions by antioxidants targeted at lysosomes causes the regression of atherosclerosis and improves liver and muscle characteristics in mice and might be a promising novel therapy for atherosclerosis in patients. NANOG Expression versus Cellular Senescence https://www.fightaging.org/archives/2021/09/nanog-expression-versus-cellular-senescence/ Are there many strategies that can reverse cellular senescence? There are certainly strategies that can lower levels of cellular senescence over time, both in cell cultures and in living an...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Acute respiratory distress syndrome is a heterogenous syndrome with many etiologies for which there are no definitive pharmacologic treatments, despite decades of research. We explore some adjunctive pharmacologic therapies, including neuromuscular blockade, corticosteroids, and inhaled pulmonary vasodilators. Additionally, we explore some investigative therapies, including Vitamin C, beta-agonists, statins, mesenchymal stromal cells, and granulocyte –macrophage colony stimulating factor. We do discuss the potential role of steroids in acute respiratory distress syndrome with severe acute respiratory syndrome coronav...
Source: Critical Care Clinics - Category: Intensive Care Authors: Source Type: research
Source: Primary Care Diabetes - Category: Primary Care Source Type: research
Source: Primary Care Diabetes - Category: Primary Care Source Type: research
Laura has not only lost a substantial amount of weight from inflammatory visceral fat resulting in a dramatic reduction in waist size, but has also experienced a reduction in the issues associated with her autoimmune diseases: “I have been on Wheat Belly for about 2 years. I have rheumatoid arthritis and lupus and have seen huge improvements and lowering of meds due to this wonderful plan. So far (and I still need to lose more) I have lost 80 lbs and am still losing. First pic is of me at our high school reunion in 2013 and the next one is today. I think you can see a bit of the difference. I am happy to be down, eve...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Wheat Belly Success Stories arthritis autoimmune gluten grains lupus rheumatoid Weight Loss Source Type: blogs
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