Dipyrone comedication in aspirin treated stroke patients impairs outcome.

CONCLUSIONS: Dipyrone comedication in patients with stroke impairs pharmacodynamic response to aspirin. This is associated with worse clinical outcome. Therefore dipyrone should be used with caution in aspirin treated stroke patients. CLINICAL TRIAL REGISTRATION: https://clinicaltrials.gov/show/NCT02148939; Identifier: NCT02148939. PMID: 27301652 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27301652?dopt=Abstract

Source: Vascular Pharmacology - June 10, 2016 Category: Drugs & Pharmacology Authors: Dannenberg L, Erschoff V, Bönner F, Gliem M, Jander S, Levkau B, Kelm M, Hohlfeld T, Zeus T, Polzin A Tags: Vascul Pharmacol Source Type: research