Liver PPAR{alpha} is crucial for whole-body fatty acid homeostasis and is protective against NAFLD

Conclusions
Altogether, these findings underscore the potential of hepatocyte PPARα as a drug target for NAFLD.

Source: Gut - June 2, 2016 Category: Gastroenterology Authors: Montagner, A., Polizzi, A., Fouche, E., Ducheix, S., Lippi, Y., Lasserre, F., Barquissau, V., Regnier, M., Lukowicz, C., Benhamed, F., Iroz, A., Bertrand-Michel, J., Al Saati, T., Cano, P., Mselli-Lakhal, L., Mithieux, G., Rajas, F., Lagarrigue, S., Pinea Tags: Nonalcoholic steatosis, Open access Hepatology Source Type: research