Vitamin E in aging persons with Down syndrome: A randomized, placebo-controlled clinical trial

Conclusions: Vitamin E did not slow the progression of cognitive deterioration in older individuals with DS. Classification of evidence: This study provides Class II evidence that vitamin E does not significantly slow the progression of cognitive deterioration in aging persons with DS.

http://www.neurology.org/cgi/content/short/86/22/2071?rss=1

Source: Neurology - May 29, 2016 Category: Neurology Authors: Sano, M., Aisen, P. S., Andrews, H. F., Tsai, W.-Y., Lai, F., Dalton, A. J., For the International Down Syndrome and Alzheimer's Disease Consortium Tags: Clinical trials Randomized controlled (CONSORT agreement), All Cognitive Disorders/Dementia, Class I ARTICLE Source Type: research