Resveratrol Attenuates Aβ25-35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway.

In conclusion, RSV attenuated neurotoxicity caused by Aβ25-35 through inducing autophagy in PC12 cells, and the autophagy was partially mediated via activation of the TyrRS-PARP1-SIRT1 signaling pathway. PMID: 27180189 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/27180189?dopt=Abstract

Source: Neurochemical Research - May 13, 2016 Category: Neuroscience Authors: Deng H, Mi MT Tags: Neurochem Res Source Type: research