A novel role for the mineralocorticoid receptor in glucocorticoid driven vascular calcification.
This study suggests that in mouse VSMCs, corticosterone acts through the MR to induce pro-calcification effects, and identifies 11β-HSD-inhibition as a novel potential treatment for vascular calcification.
PMID: 27153999 [PubMed - as supplied by publisher]
Source: Vascular Pharmacology - Category: Drugs & Pharmacology Authors: Zhu D, Rashdan NA, Chapman KE, Hadoke PW, MacRae VE Tags: Vascul Pharmacol Source Type: research
More News: Cardiology | Cardiovascular | Dexamethasone | Diabetes | Diabetes Type 1 | Drugs & Pharmacology | Endocrinology | Heart | Study