Dietary vitamin C reduced mercury contents in the tissues of juvenile olive flounder, Paralichthys olivaceus exposed with and without mercury

Publication date: Available online 10 May 2016 Source:Environmental Toxicology and Pharmacology Author(s): Jun-ho Lee, Mohammad Moniruzzaman, Hyeonho Yun, Seunghan Lee, Youngjin Park, Sungchul C. Bai A 2×3 factorial design was employed to evaluate the effects of dietary vitamin C (L-ascorblyl-2-monophosphate, C2MP) levels on growth and tissue mercury (Hg) accumulations in juvenile olive flounder, Paralichthys olivaceus. Six experimental diets with two levels of mercuric chloride (0 or 20mg HgCl2/kg diet) and three levels of vitamin C (0, 100, or 200mg C2MP/kg diet) were added to the basal diet. At the end of 6 weeks feeding trial, in presence or absence of dietary Hg, fish body weight gain, specific growth rate, feed efficiency, protein efficiency ratio and whole body lipid content were increased in a dose-dependent manner as dietary vitamin C level increased in the diets. Interestingly, fish fed 100 or 200mg C2MP/kg diets showed significant interactive effects on reducing Hg content in kidney tissue. These results revealed that dietary vitamin C as 100 or 200mg C2MP/kg diet had protective effect against Hg accumulation in juvenile olive flounder.
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research