Study Seeks Women’s Insights on What Works Best for Uterine Fibroids

Contact: Sarah Avery Phone: 919-660-1306 Email: sarah.avery@duke.edu https://www.dukehealth.org FOR IMMEDIATE RELEASE on Monday, May 9, 2016 DURHAM, N.C. – A new registry that launches this month gives women who have uterine fibroids the opportunity to help determine which strategies are most effective in treating the common condition. The registry, called Comparing Options for Management: Patient-Centered Results for Uterine Fibroids (COMPARE-UF), will enroll more than 10,000 women at clinics affiliated with nine medical centers across the country. Participating women will be asked at annual intervals specific questions about the treatments they’ve elected to receive, and how well the treatments seem to be working for them. Approximately three years after initial treatment, researchers at the Duke Clinical Research Institute (DCRI) will analyze the patients’ feedback to determine which procedures provide the greatest benefit to women – insights that have been lacking for both women and their physicians.  Specifically, studies will focus on symptom relief, reproductive effects, and effectiveness among different patient subgroups, including African-American women, who are disproportionately affected by uterine fibroids. “This is a common condition – it affects up to 75 percent of women to varying degrees and is the leading cause of hysterectomies in the country – yet we don’t know which treatment works best for a given patie...
Source: DukeHealth.org: Duke Health Features - Category: Pediatrics Tags: Duke Medicine Source Type: news

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Uterine fibroids (UF; leiomyomas) are common, benign, gynecological smooth-muscle tumors occurring in up to 80 % of women by 50 years of age [1 –4]. Symptoms include heavy menstrual bleeding (HMB), anemia, moderate/severe pain, pressure, infertility, and pregnancy complications [3–5], which have a considerable effect on women’s quality of life (QoL), causing psychological distress and placing substantial financial burden on patients a nd healthcare systems [1,6–8].
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Source Type: research
Uterine fibroids (leiomyoma) are benign monoclonal neoplasms of the myometrium and represent the most common tumors in women worldwide. Tumors occur in ∼77% of women overall and are clinically manifest in ∼25% by age 45 years. Although benign, these tumors are nonetheless associated with significant morbidity; they are the primary indication for hysterectomy, and a major source of gynecologic and reproductive dysfunction, ranging from profuse m enstrual bleeding and pelvic pain to infertility, recurrent miscarriage, and preterm labor.
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
Authors: Ciebiera M, Łoziński T Abstract Uterine fibroids (UFs) are the most common benign tumours of the female reproductive system and the most frequent reason for hysterectomy worldwide. UFs are reported in 20%-70% of women of reproductive age depending on a study group. Although most women with UFs are asymptomatic, over 30% of them will present with different symptoms. Abnormal uterine bleeding, pain, pressure and infertility are the most common. Lesions that cause these kinds of symptoms may require medical intervention. Trends in UF treatment change along with patient awareness and the introduction of new ...
Source: Ecancermedicalscience - Category: Cancer & Oncology Tags: Ecancermedicalscience Source Type: research
Abstract Ectopic pregnancy occurs when a fertilized ovum implants outside of the uterine cavity. In the United States, the estimated prevalence of ectopic pregnancy is 1% to 2%, and ruptured ectopic pregnancy accounts for 2.7% of pregnancy-related deaths. Risk factors include a history of pelvic inflammatory disease, cigarette smoking, fallopian tube surgery, previous ectopic pregnancy, and infertility. Ectopic pregnancy should be considered in any patient presenting early in pregnancy with vaginal bleeding or lower abdominal pain in whom intrauterine pregnancy has not yet been established. The definitive diagnosi...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Uterine fibroids affect up to 80% of reproductive-aged women. Although many women are asymptomatic, fibroids can cause pelvic pain, abnormal uterine bleeding, anemia, urinary frequency, infertility, and adverse pregnancy outcomes that can impair quality of life. Fifty percent of women with symptomatic fibroids report a detrimental impact on their mental and physical health (1). Fibroids appear to have a greater impact on quality of life than other chronic conditions, including asthma, irritable bowel syndrome, and gastroesophageal reflux disease (2).
Source: Fertility and Sterility - Category: Reproduction Medicine Authors: Tags: Reflections Source Type: research
ConclusionIsthmocele surgery is effective for abnormal uterine bleeding, pain and infertility regardless of the surgical route.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Publication date: Available online 30 January 2020Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Meritxell Gracia, Francisco CarmonaAbstractUterine myomas (fibroids, leiomyomas) are the most common benign myometrial tumors in women of reproductive age. They are present in 5-70% of women (depending on different series), with at least one fibroid identified in 70% of women aged 40 to 60 years. Symptoms are present in 20-50% of women with uterine fibroids and include Abnormal Uterine Bleeding (AUB), pelvic pain, Bulk-pressure symptoms and fertility problems depending on the size and ...
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Conclusion(s)Office hysteroscopy is a well tolerated procedure and prior use of analgesic medication was not effective in decreasing pain. In selected patients with chronic pelvic pain the use prior analgesic medication may be beneficial.
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research
Homœopathic Links DOI: 10.1055/s-0039-3402511Adenomyosis is a common pathological condition of the uterus where its diagnosis and treatment remain still a challenge to the treating physicians. Even though termed as benign, its clinical presentation of heavy, painful menstrual bleeding, infertility and hindrance to a women's quality of life makes it significant cause for treatment. The adenomyosis condition with significant symptoms is dealt with surgically in the conventional system of medicine by way of hysterectomy, uterine artery embolisation or endometrial ablation. These surgical interventions can be prevented w...
Source: Homoeopathic Links - Category: Complementary Medicine Authors: Tags: Case Report Source Type: research
Uterine isthmoceles are pouchlike defects in the anterior uterine wall, at the site of a prior cesarean section scar. Its prevalence has increased in direct relation to the increase in cesarean rates worldwide. Isthmoceles cause abnormal uterine bleeding, secondary infertility, and pain. There is no standard treatment for isthmoceles. This video demonstrates a robotic assisted laparoscopic approach to the resection of a uterine isthmocele.
Source: The Journal of Minimally Invasive Gynecology - Category: OBGYN Authors: Tags: Open Communications 16:  Robotics (11:00 AM – 12:45 PM) 11:35 AM Source Type: research
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