Long noncoding RNA BDNF-AS protects local anesthetic induced neurotoxicity in dorsal root ganglion neurons.

CONCLUSIONS: BDNF-AS downregulation rescued local anesthetic-induce neurotoxicity in DRG neurons, probably through the activation of neurotrophin TrkB signaling pathway. PMID: 27133058 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/27133058?dopt=Abstract

Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 30, 2016 Category: Drugs & Pharmacology Authors: Zhang Y, Yan L, Cao Y, Kong G, Lin C Tags: Biomed Pharmacother Source Type: research