Whole Exome Sequencing for Identification of Potential Causal Variants for Diffuse Cutaneous Systemic Sclerosis

Conclusion. This study demonstrates the value of WES for the identification of novel gene variants and pathways that may contribute to scleroderma risk and/or severity. The candidate genes we discovered are potential targets for in‐depth functional studies. This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatism - April 24, 2016 Category: Rheumatology Authors: Angel CY Mak, Paul LF Tang, Clare Cleveland, Melanie H Smith, M Kari Connolly, Tamiko R Katsumoto, Paul J Wolters, Pui‐Yan Kwok, Lindsey A Criswell Tags: Brief Report Source Type: research