Targeting A549 lung adenocarcinoma cell growth and invasion with protease‑activated receptor‑1 siRNA.

In conclusion, the present study demonstrated that the progression of A549 cells is able to be inhibited by knockdown of PAR1 expression. Efficient delivery of the specific siRNA targeting PAR1 may be used for further study in clinical cancer therapy.
PMID: 24604247 [PubMed - as supplied by publisher]

Source: Molecular Medicine - March 6, 2014 Category: Molecular Biology Authors: Wu Z, Zeng Y, Zhong M, Wang B Tags: Mol Med Rep Source Type: research