Diabetes and Small Vessel Cerebrovascular Disease Influence Motor and Cognitive Features in Early Parkinsons Disease (S19.006)

Conclusion: Vascular comorbidity contributes significantly to the disease pattern in patients with early PD, involving both gait and cognitive impairments. This has prognostic and treatment implications.Disclosure: Dr. Malek has nothing to disclose. Dr. Swallow has nothing to disclose. Dr. Grosset has nothing to disclose. Dr. Michael has nothing to disclose. Dr. Marrinan has received research support from GlaxoSmithKline. Dr. Bajaj has received personal compensation for activities with UCB Pharma and Eli Lilly & Company. Dr. Barker has received personal compensation for activities with National Advisory Board (UK) of SolvayHealthcare, Teva Pharmaceuticals, Daniolabs, and Synosia. Dr. Burn has received personal compensation for activities with Teva Neuroscience, Merck & Co. Inc., Serono Inc., and Boehringer Ingelheim Pharmaceuticals Inc. Dr. Hardy has received personal compensation for activities with Eisai, MRC/Wellcome, Parkinsons UK, and the Michael J Fox Foundation. Dr. Morris has received personal compensation for activities with AbbVie, UCB Pharma, and Teva Neuroscience. Dr. Williams has nothing to disclose. Dr. Wood has nothing to disclose. Dr. Ben-Shlomo has nothing to disclose. Dr. Grosset has received personal compensation for activities with AbbVie, Astellas, Civitas, and InVentiv Health as a consultant and for activities with AbbVie, GE Healthcare, Merz, Teva Neuroscience, and UCB Pharma as a speaker.

Source: Neurology - February 7, 2016 Category: Neurology Authors: Malek, N., Swallow, D., Grosset, K., Michael, L., Marrinan, S., Bajaj, N., Barker, R., Burn, D., Hardy, J., Morris, H., Williams, N., Wood, N., Ben-Shlomo, Y., Grosset, D. Tags: Movement Disorders: Parkinson ' s Disease and Atypical Parkinsonian Syndromes: Phenomenology Source Type: research