Comparison of the incidence of dientamoeba fragilis in a cohort of paediatric children with allergic asthma and aontrols: Is it a pathogen or protector?
Background: Dientamoeba fragilis is a neglected intestinal protist associated with clinical outcomes in humans. There is still an obscurity about its pathogenicity in humans, including whether it can modulate immune responses, through which mechanisms it initiates infection, or it is mostly a silent resident of human gut. There are many studies and case reports which all indicate D. fragilis as the causative agent of patients with diarhhea, abdominal pain, meteorism and urticaria. Yet, D. fragilis may have pathogenic subtypes and/or act as a pathogen under certain circumstances through interaction with the host's immune system.