Association between insulin receptor substrate-1 polymorphisms and high platelet reactivity with clopidogrel therapy in coronary artery disease patients with type 2 diabetes mellitus

The mechanisms leading to the high on-treatment platelet reactivity in diabetes patients are not fully elucidated. The genetic factors may be associated with the diminished antiplatelet efficacy of dual antipl...

Source: Cardiovascular Diabetology - March 22, 2016 Category: Cardiology Authors: Dingyu Zhang, Xiaolin Zhang, Dan Liu, Tengfei Liu, Wenzhi Cai, Chenghui Yan and Yaling Han Source Type: research