Cardiac MRI and Ischemic Heart Disease: Role in Diagnosis and Risk Stratification

Abstract Cardiac magnetic resonance imaging (CMRI) has been under development for the past four decades and has more recently become an essential tool in the evaluation of ischemic heart disease (IHD). It is the reference standard for quantification of both right and left ventricular volume and function and, after landmark work published in the New England Journal of Medicine in 2000, has proven effective in identifying hibernating myocardium, or hypokinetic myocardium that will recover after revascularization. More recent literature continues to support both delayed enhancement imaging and CMRI stress perfusion as essential tools in evaluating IHD. This review will briefly address the basics of CMRI and the scientific literature supporting the use of CMRI in IHD. It will then address more recent clinical studies establishing the clinical utility of CMRI in IHD, followed by a discussion of future directions in CMRI.
Source: Current Atherosclerosis Reports - Category: Cardiology Source Type: research

Related Links:

Ischemic heart disease remains the foremost determinant of death and disability across the world. Quantification of the ischemia burden is currently the preferred approach to predict event risk and to trigger adequate treatment. Cardiac magnetic resonance (CMR) can be a prime protagonist in this scenario due to its synergistic features. It allows assessment of wall motility, myocardial perfusion, and tissue scar by means of late gadolinium enhancement imaging. We discuss the clinical and preclinical aspects of gadolinium-based, perfusion CMR imaging, including the relevance of high spatial resolution and 3-dimensional whol...
Source: Magnetic Resonance Imaging Clinics of North America - Category: Radiology Authors: Source Type: research
ConclusionRight SCA with congenital absence of the LCA is one of the rarest coronary artery anomalies. In a significant percentage of patients it is associated with ischemia and can be life-threatening. CCTA and MRI are the modalities of choice for diagnosis and risk stratification.ResumoIntroduçãoArtéria coronária única (ACU) sem cardiopatia congénita associada é uma entidade rara. Maioria dos casos é assintomática e achados acidentais, mas podem causar isquémia, insuficiência cardíaca congestiva e morte súbita (MS).Caso clíni...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
International Study of Comparative Health Effectiveness With Medical and Invasive Approaches (ISCHEMIA) trial was sponsored by the New York University School of Medicine. Collaborators include National Heart, Lung, and Blood Institute (NHLBI), Stanford University, Duke University, Emory University, Harvard University and several other leading institutions. ISCHEMIA trial randomized 5179 patients with stable ischemic heart disease with moderate to severe degree of inducible ischemia on stress testing. Blinded CT coronary angiogram was used to exclude those with significant unprotected left main coronary artery disease or ...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: Cardiology Source Type: blogs
Estimation of left ventricular volumes, including ejection fraction (LVEF), is important in the diagnosis and the determination of severity of different cardiac diseases. Echocardiography and cardiac magnetic resonance imaging are clinically used for this purpose. However, myocardial perfusion imaging (MPI) is widely used in the diagnosis of ischemic heart disease, and the assessment of left ventricular volumes can improve the diagnostic accuracy in those patients. Development of single photon emission tomography SPECT with cadmium zinc telluride detector has improved image resolution as compared to standard sodium iodide SPECT camera.
Source: Physica Medica: European Journal of Medical Physics - Category: General Medicine Authors: Source Type: research
ConclusionsMRI represents a promising imaging modality as an initial, single-shot study, for patients with suspected PH with the advantages of being non-invasive and having no radiation exposure.
Source: Lung - Category: Respiratory Medicine Source Type: research
In this study, we asked people in an open-ended way about their desire for longer life: Would you like to have more time? What age would you like to become? This was something more specific than asking about a preference for survival without reference to any length of time; about one's plans for the future; or whether people see the future as open or limited, as in studies of future time perspective. Our attempt was to discover whether there were preferred temporal spans with which older adults framed their futures and plans. The two-question series about extra years and desired age ("How old would you like to ...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
AbstractLate gadolinium enhancement (LGE) with cardiac magnetic resonance (CMR) imaging has demonstrated the capability of stratifying hypertrophic cardiomyopathy (HCM). Stress perfusion test of CMR can quantify myocardial perfusion reserve (MPR), but its clinical role is not determined. The purpose of this study was to investigate the relationship between MPR and LGE in patients with HCM. A total of 61 consecutive cases underwent complete evaluation with electrocardiography and CMR [cine imaging, coronary MR angiography (MRA), and stress perfusion testing with LGE]. HCM cases were diagnosed by the Japanese conventional gu...
Source: Heart and Vessels - Category: Cardiology Source Type: research
Time limit: 0 Quiz-summary 0 of 20 questions completed Questions: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 Information This test series requires login for attempting. You can login easily with your Facebook account (Use the CONNECT WITH icon on the upper part of right sidebar displaying t...
Source: Cardiophile MD - Category: Cardiology Authors: Tags: General Cardiology Source Type: blogs
Cardiovascular magnetic resonance imaging has become the gold standard for evaluating myocardial function, volumes, and scarring. Additionally, cardiovascular magnetic resonance imaging is unique in its comprehensive tissue characterization, including assessment of myocardial edema, myocardial siderosis, myocardial perfusion, and diffuse myocardial fibrosis. Cardiovascular magnetic resonance imaging has become an indispensable tool in the evaluation of congenital heart disease, heart failure, cardiac masses, pericardial disease, and coronary artery disease. This review will highlight some recent novel cardiovascular magnet...
Source: Circulation: Cardiovascular Imaging - Category: Radiology Authors: Tags: Magnetic Resonance Imaging (MRI) Advances in Cardiovascular Imaging Source Type: research
ConclusionsTaken together, these data question the efficacy of phosphodiesterase type 5 inhibition to treat women with ischemic heart disease, and highlight the need for further investigation.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
More News: Cardiology | Heart | Heart Disease | MRI Scan | Perfusion | Study