Comment on: Therapeutic hypothermia for severe adult community-acquired bacterial meningitis

Kutleša et al. found that therapeutic hypothermia (TH) significantly improved outcome in patients with severe community-acquired bacterial meningitis (CABM). This retrospective study compared 41 patients treated with TH to a historic control group of 90 patients that had not been treated with TH. The use of TH reduced mortality from 48.9% to 19.5%, and improved good outcome (Glasgow Outcome Scale, 4 or 5) from 34.4% to 56.1%. We believe these results to be promising, but wish to discuss some essential issues: intracranial hypertension, brain and systemic monitoring, cooling protocol.

http://www.clineu-journal.com/article/S0303-8467(16)30025-7/abstract?rss=yes

Source: Clinical Neurology and Neurosurgery - February 28, 2016 Category: Neurosurgery Authors: Nicolas Engrand, Stéphane Welschbillig, Guillaume Taylor Tags: Discussion Source Type: research